How does sleep affect th levels of leptin and ghrelin

 Sleep affects the levels of leptin and ghrelin hormones in the following ways:

• Leptin: When a person sleeps, leptin levels normally rise, subduing the need to eat by reassuring the brain that energy reserves are adequate for the time. However, leptin levels fall with chronic sleeplessness. Unaffected leptin levels have been reported in patients with a sleep deficiency
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• Ghrelin: Ghrelin levels rise primarily in response to acute sleep deprivation, while leptin concentrations remain essentially the same. A single night of poor sleep causes acute rises in ghrelin levels, but leptin levels remain unchanged. Ghrelin is an orexigenic hormone, but increasing the appetite is not the only function it has. Instead, this hormone has many metabolic and anabolic effects in various parts of the human body. Ghrelin acts on the hypothalamic-pituitary axis and other areas of the brain to stimulate a feeling of hunger and promote feeding. Serial measurement of appetite hormones showed that ghrelin levels were significantly lower in insomnia patients, whereas leptin did not differ between the groups. Participants with short sleep had elevated ghrelin
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In summary, sleep affects the levels of leptin and ghrelin hormones by regulating their concentrations. Leptin levels rise with sleep, subduing the need to eat by reassuring the brain that energy reserves are adequate for the time. Ghrelin levels rise primarily in response to acute sleep deprivation, while leptin concentrations remain essentially the same. Ghrelin acts on the hypothalamic-pituitary axis and other areas of the brain to stimulate a feeling of hunger and promote feeding